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Genesis: The Creation and Fall
Man, in relationship to his Creator, has fallen from a place of dignity, humility and dependence to a state of depravity, pride and rebellion. This has led to unfathomable suffering. Any attempts on our own to redeem ourselves are futile, only increasing the problem of independence and self-sufficiency. Any perceived success leads only to empty vanity.
Apart from Christ, we are powerless to overcome sin, and our attempts to control it only increase our chaos.